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. 2016 Sep 8;11(9):e0162186. doi: 10.1371/journal.pone.0162186

Fig 2. Expression of α-SMA, E-cadherin, fibronectin and collagen I in the kidneys of mice with UUO.

Fig 2

Immunoperoxidase microscopy showed increased labeling intensity of α-SMA, fibronectin, and collagen I at the interstitial area in the UUO (B, J, and N) and vehicle treated UUO (C, K, and O) kidneys compared to that in the sham operated control kidneys (A, I, and M). In contrast, UUO (F) and vehicle treated UUO (G) kidneys showed decreased labeling intensity of E-cadherin compared to that in the control kidneys (E). AAT treatment reversed the changes in the labeling intensities of α-SMA, E-cadherin, fibronectin, and collagen I in the UUO kidneys (D, H, L, and P).