Figure 5.

AOX rescues diverse developmental abnormalities produced by tubGS. Proportion of progeny hemizygous for both tubGS and the indicated transgenes, which exhibited the indicated developmental abnormalities, when reared on food containing 10 μM RU486. The total numbers of flies of each genotype analyzed, in a single large-scale experiment (n), is as shown. See supplemental material for a detailed description of phenotypic categories. Asterisks indicate significant differences (P < 0.001) from the w¹¹¹⁸ background strain hemizygous for tubGS, based on chi-squared analysis for each phenotypic category or for the four thoracic phenotypes (normal thorax, malformed scutellum, mild cleft, and severe cleft) considered as a whole. AOX, alternative oxidase; tubGS; α-tubulin-GeneSwitch.