Table 1. T. pallidum proteins found in previous proteome investigation (McGill et al.) [16] but not detected in this study.
| TP number | UniProt Accession Number# | Protein Name(s) | Molecular Weight (kDa) | COG category code | cDNA/DNA signal ratio Smajs et al. [15] |
|---|---|---|---|---|---|
| TP0112 | O83150 | Aminopeptidase C (PepC)/Bleomycin hydrolase | 51 | none | 1.0 |
| TP0139 | O83175 | Trk family potassium (K+) transporter, NAD+ binding protein | 25 | P | 0.6 |
| TP0201 | R9UV93 | 50S ribosomal protein L5 | 21 | none | 1.8 |
| TP0216 | R9UVA6 | Chaperone protein DnaK/Heat shock 70 kDa protein | 68 | none | 4.5 |
| TP0239 | R9UU25 | 50S ribosomal protein L10 | 20 | none | 1.9 |
| TP0259 | O83283 | Peptidoglycan binding (LysM domain-bacterial cell wall degradation) | 29 | S | 5.4 |
| TP0298 | R9UW99 | ABC superfamily ATP binding cassette transporter, membrane protein/ Membrane lipoprotein TpN38 | 38 | none | 3.3 |
| TP0349 | R9UUA6 | Peptidyl-prolyl cis-trans isomerase/ Metallochaperone SlyD | 18 | O | 2.2 |
| TP0356 | O83375 | Putative RNA-binding protein | 12 | none | 10.7 |
| TP0424 | R9UWN5 | Two-sector ATPase, V(1) subunit E | 19 | none | 4.7 |
| TP0435 | R9UWP1 | Copper resistance lipoprotein NlpE/17 kDa lipoprotein | 17 | none | 5.1 |
| TP0448 | R9UUM3 | Uracil phosphoribosyltransferase | 41 | F | 0.3 |
| TP0453 | O67998 | Outer membrane protein/30kLp | 32 | none | 1.0 |
| TP0476 | R9UWS9 | Acetate kinase/Acetokinase | 49 | none | 1.3 |
| TP0505 | O83518 | Hexokinase | 48 | none | 1.8 |
| TP0537 | R9UTC2 | Triosephosphate isomerase | 27 | G | 1.9 |
| TP0554 | O83565 | Phosphoglycolate phosphatase | 25 | R | 1.1 |
| TP0556 | R9UWZ4 | Aspartate—ammonia ligase/Asparagine synthetase A | 37 | E | 1.8 |
| TP0584 | R9UTG3 | Uncharacterized protein | 54 | none | 0.8 |
| TP0611 | O83620 | ABC superfamily ATP binding cassette transporter, ABC protein | 28 | none | 1.2 |
| TP0655 | O83661 | Spermidine/putrescine ABC superfamily ATP binding cassette transporter, binding protein | 40 | E | 0.6 |
| TP0734 | R9UXE0 | Purine-nucleoside phosphorylase | 25 | F | 1.6 |
| TP0769 | R9UTV1 | Treponemal membrane protein B/ Antigen TmpB | 37 | S | 5.2 |
| TP0821 | R9UVI4 | Lipoprotein/ Membrane lipoprotein TpN32; 29 kDa protein | 29 | P | 1.5 |
| TP0823 | O83795 | Desulfoferrodoxin (Rbo) | 14 | C | 3.2 |
| TP0862 | O83834 | Peptidyl-prolyl cis-trans isomerase | 28 | none | 5.3 |
| TP0925 | R9UUA1 | Nitrogenase (Flavodoxin) | 16 | C | 9.4 |
| TP0964 | O83930 | ABC transporter, ATP-binding protein | 25 | V | 0.9 |
| TP0971 | R9UX80 | Tp34 lipoprotein/ 34kDa membrane antigen | 22 | none | 12.6 |
| TP1013 | R9UUH7 | 10 kDa chaperonin/GroES protein/Protein Cpn10 | 9 | O | 4.6 |
Legend:
#: UniProt Proteome ID: UP000014259; Clusters of Orthologous Genes (COG)