Figure 1.
Chronic hyperglycemia impairs NOS-mediated dilation of retinal arterioles. Concentration-dependent dilation of isolated retinal arterioles to bradykinin was examined in the absence or presence of NOS inhibitor L-NAME after 2 weeks of euglycemia (Control; n = 6) or hyperglycemia (Diabetes; n = 9) in pigs. *P < 0.05 versus Control; #P < 0.05 versus Control or Diabetes.
