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. 2016 Aug 29;57(10):4412–4419. doi: 10.1167/iovs.15-17784

Figure 5.

Figure 5

The myopic shift (OD minus OS) induced by FD treatment is shown for the two genotypes, Ctrl (A) and rTHKO (B). The dashed lines show data for the FD treated mice, while the solid lines represent data from the naïve, untreated mice. (A) Control mice undergoing the FD treatment showed a significant myopic shift after 2 weeks of treatment (two-way repeated measures ANOVA interaction effect: F(3,90) = 5.54, P < 0.01; post hoc analysis: *P < 0.05; **P < 0.01; ***P < 0.001). All goggled time-points have greater than three Ctrl mice except at 10 weeks. (B) Retina-specific THKO mice undergoing the FD treatment showed a myopic shift after 2 weeks of treatment (two-way repeated measures ANOVA main effect of treatment: F(1,93) = 11.1, P < 0.01). Symbols represent average ± SEM.