Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jun 23;291(33):17143–17164. doi: 10.1074/jbc.M116.732966

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 10. — Reaction products formed from 17α-hydroxyprogesterone and 17α-hydroxypregnenolone in P450 17A1 reactions supported by various factors. Retention times (t_R) and integration units are indicated on the chromatograms. A–C, 17α-hydroxyprogesterone; D–F, 17α-hydroxypregnenolone. A and D, NADPH-P450 reductase, cytochrome b₅, and NADPH; B and E, H₂O₂ (10 mm) (with cytochrome b₅); C and F, iodosylbenzene (PhI=O, 300 μm) (with cytochrome b₅). In these studies the Δ⁵ products (formed from 17α-hydroxypregnenolone) were oxidized to Δ⁴ products to facilitate LC-UV analysis.