FIGURE 5.
Neuritin has the same effect on IA densities and Kv4.2 protein expression in cortical neuron. A, induction of IA densities by current recording in C57BL/6 mouse cortical neurons upon neuritin stimulation. The upper panel shows a representative sample, and statistical analysis is shown in the lower panel. ***, p < 0.001 compared with corresponding control by unpaired t test. B, Kv4.2 protein expression by Western blotting in C57BL/6 mouse cortical neurons upon neuritin stimulation. *, p < 0.05 compared with value 1 as the hypothetical mean by one-sample t test. The upper panel shows a representative sample, and statistical analysis is shown in the lower panel. C, expression level of neuritin after AAV-control and AAV-neuritin virus injected bilaterally into the PFC for 2 weeks was determined by Western blotting. ***, p < 0.001 compared with value 1 as the hypothetical mean by one-sample t test.