FIGURE 6.

Requirement of NFATc4 in neuritin-mediated neuronal excitability in PFC neurons of mice. A, effect of AAV-mediated neuritin expression on AP firing frequency in C57BL/6 and Nfatc4^−/− mouse cortical neurons. B, effect of AAV-mediated neuritin expression on the latency of the first AP in C57BL/6 and Nfatc4^−/− mouse cortical neurons. C and D, effect of AAV-mediated neuritin expression on injected current to evoke the first AP and interevent interval in C57BL/6 and Nfatc4^−/− mouse cortical neurons. ***, p < 0.01 for two groups connected with a straight line by one-way ANOVA followed by Fisher's post hoc test.