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. 2016 Jul 5;291(34):17692–17705. doi: 10.1074/jbc.M116.719971

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FIGURE 5. — Chemically induced mutation accumulation. A, summary of the mutations in the MNNG- and EMS-treated strains. Each background contained five replicates, and mutations were combined for calculations. B, mutation rate for single-nucleotide substitutions (blue) and indels (orange) in MNNG-treated strains. The green line represents the ratio of indels/single-nucleotide substitutions. C, mutation rate for single-nucleotide substitutions (blue) and indels (orange) in EMS-treated strains. The green line represents the ratio of indels/single-nucleotide substitutions.