TABLE 1.

Generation estimates for single cell bottleneck passages

Diameter	Cell number	Generation
		Duplicates	Average
mm
1.0	1,050,000	20.00	19.91
	925,000	19.82
1.5–1.7	3,175,000	21.6	21.4
	2,425,000	21.21
1.5	2,700,000	21.36	21.2
	2,150,000	21.04
0.8	525,000	19.00	19.35
	850,000	19.7