Table 1.

Nanoparticles for delivery of PNA

Nanoparticles	Applications	Study design	Ref
PLGA	Gene editing	Cell culture (CD34+ and THP1) Preclinical (in mice)	[26–28]
	Antisense	Cell culture (THP1 and HeLa)	[29]
Peptide coated PLGA	Antisense	Preclinical (in mice)	[30]
PBAE/PLGA	Gene editing	Preclinical (in mice)	[27]
MPG coated PBAE/PLGA	Gene editing	Preclinical (in mice)	[31]
Avidin-labeled nanoparticles	Delivery vehicle	Preliminary characterization	[32]
Zeolites-L-Nanocrystals	Delivery vehicle	Cell culture (HeLa)	[33]
Mesoporous silica nanoparticles	Antisense	Cell culture (HeLa)	[34]
Cationic shell cross-linked knedel-like nanoparticles	Antisense	Preclinical (in mice)	[35, 36]
	Splice correction	Cell culture (HeLa)	[37]
	Imaging mRNAs	Cell culture (RAW 264.7)	[38, 39]
Gold nanoparticles	RNA detection	Cell culture (Vero cells)	[40]
Cobalt ferrite core/metallic shell	PNA/DNA based biosensors	Solution based in vitro assay	[41]