Table 3. Post-diagnosis body mass index (BMI) and mortality outcomes (N=3,157).
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| N | Event | Age, race, sex adjusted HR | 95% CI | MV-adjusted HR | 95% CI | |
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| All-cause mortality | ||||||
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| BMI (kg/m2) | ||||||
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| <18.5 | 78 | 38 | 3.71 | (2.52, 5.45) | 3.38 | (2.19, 5.20) |
| 18.5-<23 | 539 | 108 | Ref | Ref | ||
| 23-<25 | 411 | 60 | 0.70 | (0.51, 0.96) | 0.72 | (0.52, 1.02) |
| 25-<28 | 721 | 90 | 0.56 | (0.42, 0.75) | 0.56 | (0.41, 0.77) |
| 28-<30 | 396 | 44 | 0.46 | (0.32, 0.66) | 0.39 | (0.26, 0.58) |
| 30-<35 | 643 | 78 | 0.57 | (0.42, 0.77) | 0.51 | (0.35, 0.73) |
| 35+ | 400 | 72 | 0.96 | (0.70, 1.30) | 0.85 | (0.56, 1.30) |
| CRC-specific mortality | ||||||
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| <18.5 | 78 | 25 | 3.25 | (2.00, 5.27) | 3.21 | (1.88, 5.47) |
| 18.5-<23 | 539 | 70 | Ref | Ref | ||
| 23-<25 | 411 | 38 | 0.70 | (0.47, 1.04) | 0.69 | (0.46, 1.05) |
| 25-<28 | 721 | 53 | 0.53 | (0.37, 0.76) | 0.50 | (0.34, 0.75) |
| 28-<30 | 396 | 30 | 0.53 | (0.34, 0.82) | 0.42 | (0.26, 0.67) |
| 30-<35 | 643 | 60 | 0.67 | (0.47, 0.96) | 0.56 | (0.36, 0.85) |
| 35+ | 400 | 45 | 0.86 | (0.59, 1.27) | 0.84 | (0.51, 1.37) |
*
Age-adjusted HR adjusted for age (continuous), sex, and race (White (ref), Black, Hispanic, Asian/Pacific Islander, Other). MV-adjusted analysis adjusted additionally for stage (I (ref), II, III), grade (1, 2 (ref), 3, 4), chemotherapy (no (ref), yes), radiation (no (ref), yes), disease site (proximal (ref), distal, rectal), smoking (never (ref), past, current), physical activity (0, >0 to <120, 120+ minutes/wk), and pre-diagnosis BMI (<18.5, 18.5-<23 (ref), 23-<25, 25-<28, 28-<30, 30-<35, 35+ kg/m2).