Table 2.

Differences in hemodynamic parameters between study days and between baseline and during infusions.

Parameters	Intact		Autonomic Blockade		p (saline-trimt)

	Baseline	Saline	Baseline	Trimethaphan
SBP, mm Hg	153 ± 5.0	153 ± 5.2	156 ± 5.3	111 ± 4.5^0.003	0.003
DBP, mm Hg	88 ± 3.0	89 ± 3.2	90 ± 3.8	70 ± 2.8^0.003	0.003
HR, bpm	65 ± 3.6	62 ± 2.4	65 ± 3.5	78 ± 2.6^0.003	0.008
CO, L/min	6.2 ± 0.6	6.5 ± 0.6	6.6 ± 0.7	5.7 ± 0.4	0.779
SV, mL	94 ± 5.7	97 ± 5.6	99 ± 7.3	77 ± 3.8^0.016	0.05
TPR, dyn×sec×cm⁻⁵	1571 ± 128	1503 ± 121	1567 ± 131	1255 ± 86.3^0.021	0.036
MAP	110 ± 3.3	111 ± 3.5	112 ± 4.0	84 ± 3.1^0.003	0.003
FBF	2.8 ± 0.3	3.2 ± 0.4	3.2 ± 0.4	5.4 ± 0.7^0.001	0.016
FVR	49.7 ± 7.4	42.5 ± 6.7	44.8 ± 6.8	20.0 ± 3.2^0.003	0.004
FVC	2.5 ± 0.3	2.9 ± 0.4 ^*^0.041	2.6 ± 0.3	1.97 ± 0.8^0.003	0.004

Values are expressed as mean ± S.E.M. The “p (before-after)” column reflects differences between study days (intact vs. blocked) during the infusions (saline or trimethaphan)

p <0.05 for the comparison between baseline and infusion for each study day.

No significant differences were observed between study days at baseline.