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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Hypertension. 2016 Aug 1;68(4):949–955. doi: 10.1161/HYPERTENSIONAHA.116.07620

Figure 1.

Figure 1

Prevention of cardiovascular remodeling in VSMC ADAM17 deficient mice. VSMC ADAM17 deficient mice (A17f/fsmCre+/−) and control littermate mice (A17f/fsmCre−/−) were infused with AngII or saline for 2 weeks. A: Tissues (heart and kidney) were stained with Sirius Red. Representative images are shown. Data are mean±SEM (n=6). B: Heart weight body weight ratio was calculated. Mean±SEM (n=8). C: Mean arterial blood pressure was evaluated by telemetry. Mean±SEM (n=8). *p<0.05 compared with saline control. †p<0.05 compared with AngII control.