Table 2.
Comparison between TNBS and DSS models of colitis and the control groups in terms of pulmonary tissue VEGF and TNF-α concentrations and alveolar hemorrhage
| Variable | TNBS-model |
DSS-model |
||||
|---|---|---|---|---|---|---|
| Colitis (n = 6) | Control (n = 6) | p value | Colitis (n = 6) | Control (n = 6) | p value | |
| Alveolar hemorrhage | 5 | 1 | 0.015 | 5 | 1 | 0.015 |
| VEGF, pg/mg | 39.8 ± 3.0 | 22.5 ± 4.6 | 0.002 | 29.8 ± 11.2 | 17.9 ± 2.8 | 0.004 |
| TNF-α, pg/mg | 36.3 ± 4.6 | 20.6 ± 5.4 | 0.002 | 44.3 ± 8.7 | 22.7 ± 3.9 | 0.002 |
Values are presented as mean ± SD.
TNBS, trinitrobenzene sulfonic acid; DSS, dextran sulphate sodium; VEGF, vascular endothelial growth factor; TNF-α, tumor necrosis factor α.