Table 2.
Multiple logistic regression analysis of factors that increased the risk of incomplete recovery after acute kidney injury
| Variable | Unadjusted |
Adjusted |
Fully adjusted |
|||
|---|---|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
| Age, yr | 1.061 (1.009–1.116) | 0.021 | 1.198 (1.063–1.351) | 0.003 | 1.231 (1.041–1.457) | 0.015 |
| Male sex | 0.462 (0.152–1.407) | 0.174 | 0.495 (0.062–3.919) | 0.505 | ||
| Baseline condition | ||||||
| Diabetes | 0.568 (0.154–2.096) | 0.396 | 0.822 (0.085–7.920) | 0.866 | ||
| Hypertension | 1.636 (0.533–5.019) | 0.389 | 1.099 (0.157–7.716) | 0.924 | ||
| AKI cause, % | ||||||
| Ischemic ATN | 4.714 (0.868–25.612) | 0.073 | 10.185 (0.905–114.630) | 0.060 | 10.073 (0.402–252.144) | 0.160 |
| Infection-related ATN | 3.000 (0.493–18.247) | 0.233 | 1.081 (0.102–11.469) | 0.948 | 0.669 (0.029–15.459) | 0.802 |
| CRRT duration, hr | 1.012 (1.003–1.022) | 0.013 | 1.023 (1.004–1.043) | 0.020 | 1.024 (1.000–1.050) | 0.052 |
| Anuria duration, 6 hr | 1.038 (1.010–1.066) | 0.007 | 1.059 (1.007–1.114) | 0.026 | 1.064 (1.001–1.131) | 0.047 |
| Initial hemoglobin, g/dL | 0.909 (0.724–1.142) | 0.414 | 0.879 (0.592–1.305) | 0.523 | ||
| Initial CRP, mg/dL | 0.986 (0.938–1.035) | 0.563 | 1.005 (0.890–1.135) | 0.934 | ||
| Initial eGFR, mL/min/1.73 m2 | 0.983 (0.936–1.033) | 0.495 | 0.999 (0.910–1.097) | 0.986 | ||
| Average MAP, mmHg | 0.972 (0.917–1.031) | 0.341 | 1.012 (0.884–1.159) | 0.862 | ||
| Volume balance, mL | 1.000 (1.000–1.000) | 0.706 | 1.000 (1.000–1.000) | 0.436 | ||
OR, odds ratio; CI, confidence interval; AKI, acute kidney injury; ATN, acute tubular necrosis; CRRT, continuous renal replacement therapy; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; MAP, mean arterial pressure.