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. 2016 Feb 3;31(5):995–998. doi: 10.3904/kjim.2015.065

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Copyright © 2016 The Korean Association of Internal Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Histology of the brain biopsy. (A) The lesion shows a large number of gitter cells (foamy macrophages) infiltrating with a relatively sharp border with the normal area (H&E, ×50). (B) Normal area shows intact myelinated nerve fibers on Luxol fast blue (LFB) staining (×200). (C) The lesion shows near-complete loss of myelinated nerve fibers with heavy macrophage infiltration compared to the normal area (LFB stain, ×200). (D) Neurofilament stain (×100) of the lesion shows relatively intact axons.