Figure 2.

Pattern of tissue-invasive cytomegalovirus (CMV) disease in allogeneic hematopoietic stem cell transplant (HCT) recipients during preemptive therapy. (A) It shows the pattern of 10 HCT recipients (48%) with CMV disease were classified as group A (abrupt onset of CMV disease before or during antiviral therapy), while (B) shows the other 11 (52%) as group B (successful antiviral therapy followed by CMV disease). Median post-HCT days of the first episodes of CMV disease in group A and group B were 40 (interquartile range [IQR], 27 to 51) and 110 (IQR, 76 to 140), respectively (p < 0.001). A plain figure without borderline lying on the patient number means a type of preceding CMV antigenemia: a circle, no preceding CMV antigenemia; a triangle, preceding nonsignificant CMV antigenemia (< 5/200,000 cells); a rectangle, preceding significant CMV antigenemia (≥ 5/200,000 cells). A plain figure with a thick borderline means time of diagnosis and type of tissue-invasive CMV disease. A number written below plain figure of HCTA8 means time of diagnosis of tissue-invasive CMV diseases developing more than 180 days post-HCT.