Table 3.
Risk factors for pancreatic fistula according to univariate analysis
| Variable | POPF occurrence |
|||
| Yes | No | χ2 | P value | |
| Sex | 7.042 | 0.008 | ||
| Male | 186 | 157 | ||
| Female | 83 | 113 | ||
| Age (yr) | 2.132 | 0.144 | ||
| ≥ 60 | 99 | 116 | ||
| < 60 | 170 | 154 | ||
| Body mass index (kg/m2) | 5.066 | 0.024 | ||
| > 25 | 85 | 62 | ||
| ≤ 25 | 184 | 208 | ||
| Hypertension | 0.938 | 0.332 | ||
| Yes | 62 | 53 | ||
| No | 207 | 217 | ||
| Diabetes mellitus | 3.941 | 0.047 | ||
| Yes | 29 | 45 | ||
| No | 240 | 225 | ||
| Drinking history | 0.169 | 0.681 | ||
| Yes | 77 | 73 | ||
| No | 193 | 197 | ||
| Smoking history | 1.426 | 0.232 | ||
| Yes | 78 | 66 | ||
| No | 191 | 204 | ||
| Epigastrium surgery | 0.640 | 0.424 | ||
| Yes | 18 | 23 | ||
| No | 251 | 247 | ||
| Preoperative biliary drainage | 0.406 | 0.524 | ||
| Yes | 65 | 59 | ||
| No | 204 | 211 | ||
| Preoperative total bilirubin (μmol/L) | 0.378 | 0.539 | ||
| > 171 | 73 | 67 | ||
| ≤ 171 | 196 | 203 | ||
| Serum albumin (g/L) | 0.000 | 0.985 | ||
| < 35 | 41 | 41 | ||
| ≥ 35 | 228 | 229 | ||
| Blood glucose (mmol/L) | 9.157 | 0.002 | ||
| ≤ 6.0 | 190 | 157 | ||
| > 6.0 | 79 | 113 | ||
| Pancreaticojejunostomy | 20.323 | 0.000 | ||
| Double-layer mucosa-to-mucosa | 229 | 169 | ||
| Single-layer mucosa-to-mucosa | 50 | 91 | ||
| Blood loss (mL) | 0.134 | 0.715 | ||
| > 600 | 34 | 37 | ||
| ≤ 600 | 235 | 225 | ||
| Pancreatic duct diameter (mm) | 19.687 | 0.000 | ||
| ≤ 3 | 185 | 135 | ||
| > 3 | 84 | 135 | ||
| Pylorus-preserving | 0.017 | 0.897 | ||
| Yes | 131 | 133 | ||
| No | 138 | 137 | ||
| Pancreatic duct drainage | 0.016 | 0.900 | ||
| External | 64 | 63 | ||
| Enteral | 205 | 207 | ||
| Intraoperative blood infusion | 1.310 | 0.252 | ||
| Yes | 36 | 46 | ||
| No | 233 | 224 | ||
| Operative time (min) | 0.299 | 0.584 | ||
| > 300 | 196 | 191 | ||
| ≤ 300 | 73 | 79 | ||
| Braun anastomosis | 2.274 | 0.132 | ||
| Yes | 78 | 94 | ||
| No | 192 | 175 | ||
| Pancreatic texture | 29.330 | 0.000 | ||
| Soft | 228 | 174 | ||
| Hard | 41 | 96 | ||