Table 3.
Type 1 and type 2 diabetes and risks of pre-eclampsia subtypes
| Pre-eclampsia subtype | Diabetic disease | Total (n) | Pre-eclampsia | ||||
|---|---|---|---|---|---|---|---|
| n | % | Crude OR (95% CI) | Adjusted OR (95% CI) | ||||
| Model 1a | Model 2b | ||||||
| Mild/moderate | No | 1,509,525 | 28,460 | 1.9 | 1.00 | 1.00 | 1.00 |
| Type 1 | 7062 | 704 | 10.0 | 5.69 (5.24, 6.19) | 5.08 (4.65, 5.56) | 4.89 (4.45, 5.38) | |
| Type 2 | 886 | 58 | 6.5 | 3.44 (2.58, 4.58) | 2.01 (1.50, 2.68) | 2.18 (1.50, 3.16) | |
| Severe | No | 1,509,525 | 13,574 | 0.9 | 1.00 | 1.00 | 1.00 |
| Type 1 | 7062 | 399 | 5.6 | 6.51 (5.84, 7.25) | 5.95 (5.29, 6.69) | 5.75 (5.08, 6.52) | |
| Type 2 | 886 | 28 | 3.2 | 3.50 (2.37, 5.16) | 2.29 (1.53, 3.45) | 2.45 (1.47, 4.07) | |
| Preterm (<37 weeks) | No | 1,509,525 | 9360 | 0.6 | 1.00 | 1.00 | 1.00 |
| Type 1 | 7062 | 435 | 6.2 | 10.35 (9.29, 11.52) | 9.08 (8.06, 10.22) | 8.72 (7.68, 9.89) | |
| Type 2 | 886 | 27 | 3.1 | 4.74 (3.13, 7.16) | 3.11 (2.05, 4.70) | 3.22 (1.93, 5.37) | |
| Term (≥37 weeks) | No | 1,509,525 | 32,674 | 2.2 | 1.00 | 1.00 | 1.00 |
| Type 1 | 7062 | 668 | 9.5 | 4.65 (4.27, 5.06) | 4.30 (3.93, 4.71) | 4.19 (3.81, 4.62) | |
| Type 2 | 886 | 59 | 6.7 | 3.06 (2.32, 4.03) | 1.80 (1.36, 2.40) | 1.96 (1.36, 2.82) | |
aAdjusted for maternal BMI (kg/m2)
bAdjusted for maternal BMI, height, age, parity, education, smoking and country of birth