Table 1: Summary of Antiarrhythmic Drug Dosages Applied in Clinical Trials.

Antiarrhythmic Drug	References	Dosage	Notes
Amiodarone	15,17–19	200 mg once daily	Saturation dose 10–12 g
Sotalol	17–21	160 mg twice daily	Care should be taken to monitor for renal dysfunction
Ranolazine	32–35	375 mg twice daily	Applied in addition to sotalol or amiodarone
Dofetilide	23–25	500 µg once daily	Care should be taken to monitor for renal dysfunction
Azimilide	15,22	175 mg once daily	Not clinically available
Dronedarone	26,27	400 mg twice daily	Contraindicated in patients with heart failure
Mexilitine	28–29	100 mg twice daily	Applied in addition to amiodarone