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. 2016 Jul 22;291(37):19374–19386. doi: 10.1074/jbc.M116.725903

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© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 9. — Glucocorticoids protect cardiomyocytes from DNA degradation triggered by doxorubicin. NTC, (−)GR, and (−)KLF13 cells were culture with dexamethasone for 48 h, and then treated with 1 μm Dox for 48 h. Cell viability and DNA damage were analyzed by flow cytometry. A, percentage (%) of dead cells in each group treatment. B, the plot represents the percentage (%) of degraded DNA in each group treatment. Data are represented as the mean ± S.E. from three independent experiments. *, p < 0.05; **, p < 0.01; ***, p < 0.001; ns, no significant.