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Model of eEF2K medicated cell death machinery in response to DNA damage. eEF2K has two roles in cell death induced by DNA damage; one is to promote apoptosis, and the other is to control cell cycle arrest to prevent mitotic cell death. When mitotic catastrophe takes charge, pro-apoptotic eEF2K will switch to being an anti-death protector by arresting the cell cycle to suppress mitotic catastrophe.
