FIGURE 10.
2-Deoxyglucose collapses mitochondrial membrane potential after respiratory inhibition in ANT2/3 single and double knockdown cells. MYX and 2DG were added sequentially to A549 cells after 48 h of siRNA knockdown of ANT2 (A), ANT3 (B), and both ANT2 and ANT3 (C). Average intensity of TMRM fluorescence after knockdowns is plotted in comparison with non-target (D). *, p < 0.05 versus Baseline; †, p < 0.05 versus MYX.