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Bongkrekic acid and carboxyatractyloside inhibit respiration in permeabilized cancer cells. HepG2 cells were permeabilized with digitonin (DIG, 10 μm) in intracellular buffer as described under “Experimental Procedures.” OLIG, BA, CAT, or vehicle (VEH) was added as indicated. Digitonin (DIG) was not added in VEH-treated group.
