Table 2.

ADL scores for age-matched controls, patients with attenuated phenotypes, and patients with severe phenotypes.

		Subject age range (years)
		0–5	5–10	10–15	15–20	20<
Control	n	42	58	26	5	14
	Movement	14.57 ± 6.26	19.40 ± 0.56	19.96 ± 0.20	20.00 ± 0.00	20.00 ± 0.00
	Movement Cognition	8.79 ± 6.54	19.19 ± 1.89	19.88 ± 0.43	20.00 ± 0.00	20.00 ± 0.00
	Cognition	8.38 ± 5.49	15.93 ± 2.55	18.81 ± 1.83	20.00 ± 0.00	20.00 ± 0.00
Severe	n	7	4	11	13	28
	Movement	12.43 ± 4.50	14.88 ± 2.66	10.68 ± 4.05	8.46 ± 4.67	8.23 ± 5.32
	pa	0.3908	p < 0.0001	p < 0.0001	p < 0.0001	p < 0.0001
	Movement with Cognition	11.00 ± 6.76	14.13 ± 4.94	13.77 ± 2.09	12.88 ± 4.10	12.46 ± 5.78
	pa	0.4129	p < 0.0001	p < 0.0001	p < 0.005	p < 0.0001
	Cognition	14.00 ± 8.10	19.75 ± 0.50	19.27 ± 2.10	19.38 ± 1.19	18.23 ± 2.69
	pa	p < 0.05	p < 0.005	0.5038	0.2743	p < 0.05
Attenuated	n	-	3	1	3	10
	Movement	-	16.33 ± 3.06	18.00	14.50 ± 3.50	13.25 ± 3.58
	pa	-	p < 0.0001	NA	p < 0.01	p < 0.0001
	Movement with Cognition	-	19.67 ± 0.58	18.00	17.33 ± 2.31	17.70 ± 2.06
	pa	-	0.6661	NA	p < 0.05	p < 0.001
	Cognition	-	20.00 ± 0.00	20.00	20.00 ± 0.00	19.70 ± 0.67
	pa	-	p < 0.01	NA	NA	0.1074
t-Test between phenotypes	Movement	-	0.5289	NA	0.0559	p < 0.01
	Movement with Cognition	-	0.1177	NA	0.0961	p < 0.01
	Cognition	-	0.4366	NA	0.3990	0.0986

^aControl vs. severe or attenuated phenotype.

NA: not applicable.