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. 2016 Sep 9;6:33172. doi: 10.1038/srep33172

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Copyright © 2016, The Author(s)

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(a) Increase in lipid peroxidation in the mouse hippocampus. ANOVA: F_(3,22) = 52.2, p < 0.0001, ***p < 0.001 vs. the Sc.Aβ/V-treated group; ^###p < 0.001 vs. the Aβ_25-35/V-treated group; Dunnett’s test (b) increase in TNFα levels in the mouse hippocampus. ANOVA: F_(3,22) = 2.47, p > 0.05. Note that a Dunnett’s test between the Sc.Aβ- and Aβ_25-35-treated groups led to a significant (p < 0.05) difference (c) decrease of synaptophysin level in the mouse hippocampus. ANOVA: F_(3,22) = 9.15, p < 0.001, **p < 0.01, ***p < 0.001 vs Sc.Aβ/V, ^##p < 0.01 vs Aβ_25-35/V; Dunnett’s test. V, vehicle solution. N = 5–7 per group.