| Multivariate |
| Natalie Reimers-10 |
Breast carcinoma |
ER, PR (inversely) |
High tumor grade, histologically determined mitotic index, tumor size, inversely correlated to age |
| HC Zheng-19 |
Gastric carcinoma |
ki-67, MMP-2, MMP-9, VEGF, MVD |
Tumour size, depth of invasion, lymphatic invasion, not with lymph node metastasis, UICC staging or differentiation |
| Kazu Ueda-20 |
Endometrial carcinoma |
|
Advanced stage, poorly differentiated carcinoma, lymph node metastasis, lymphatic vessel infiltration, pathological high risk group |
| Qing Zhang-21 |
Hepatocellular carcinoma |
MVD-CD34; MMP-2 in pericancerous, not in cancerous lesions; VEGF |
pTNM tumor stages, tumor size and venous invasion, IV stage and large tumor size, preoperative AFP level; not: viral hepatitis, the number of tumor nodules, lymph node metastasis |
| Anne B. Als-5 |
Bladder Cancer |
|
Visceral metastases |
| Wulf Sienel-22 |
Non-small-cell lung cancer |
MMP-2 (no), MMP-9 (no) |
|
| Xingzhu Ju-23 |
Cervical Cancer |
|
Pelvic lymph node metastasis, no correlation with clinical stage and histopathology |
| Yu Li-11 |
Breast carcinoma |
|
|
| Fangfang Liu-12 |
Breast carcinoma |
C-erbB-2; ER, PR (inversely) |
Histological grade, local recurrence, distant metastasis and tumor mortality |
| Xinjie Yang-24 |
Adenoid cystic carcinoma of salivary glands |
MMP-2, MMP-9, VEGF, Ki-67 index, MVD |
Tumor size, histotypes, clinical stage, perneural invasion, vascular invasion, metastasis |
| Wei-De Zhong-25 |
Bladder cancer |
|
Tumor stage and grade, status of carcinoma in situ, tumor recurrence, tumor progression |
| Tongwei Chu-26 |
Pediatric Medulloblastoma |
|
Higher metastatic stage, aggressive histopathological type, necrosis, undifferentiated tumor |
| Yijun Xue-27 |
Bladder cancer |
|
Lymph node status, tumor stage, histologic grade |
| Shaojun Zhu-28 |
Esophageal Squamous Cell Carcinoma |
|
Lymph node metastasis cases, differentiation, depth of tumor invasion |
| Weide Zhong-29 |
Prostate cancer |
|
Gleason score, positive surgical margin status, reduced PSA failure-free survival |
| Xuecheng Bi-30 |
Human seminomas |
MMP-2 |
advanced T, N and M stage, poor differentiation types |
| K Boye-31 |
Colorectal cancer |
S100A4 |
no associations with any of the clinical or histopathological parameters |
| Zhangxuan Shou-32 |
Gastric Cancer |
ADAM17 |
Age, tumor size, location, depth of invasion, TNM stage, Lauren’s classification, vessel invasion, and lymph node and distant metastasis of tumor |
| Albrecht Stenzinger -33 |
Colorectal cancer |
|
Trend correlation with stage, distant metastasis, blood vessel invasion, and Dukes classification |
| Shuhua Zhao-13 |
Ovarian cancer |
|
Lymph-vascular space involvement, lymph node metastasis |
| Ying Liu-34 |
Breast cancer |
|
|
| Anja Rabien-35 |
Renal cell carcinoma |
|
pT stage and Fuhrman grading |
| Xiaoyan Xu-36 |
Non-small lung cancer |
|
Tumor diameter, lymph node status, tumor stage |
| Min Yang-37 |
Glioblastoma |
|
Karnofsky performance status (KPS) score |
| Yang Zhao-14 |
Ovarian carcinomas |
Ki-67 |
FIGO staging, dedifferentiation |
| Qiang Lu-17 |
Osteosarcoma |
|
Pathological classification, percentage of dead cells |
| Dake Chu-38 |
Gastric cancer |
|
Invasion, metastasis and TNM stage |
| Qin Xu-39 |
Cervical carcinoma |
|
FIGO clinical stage, lymph node metastasis, parametrium invasion, and differentiation |
| Shu Zhao-40 |
Breast cancer |
MMP-9, Ki67 |
Lymph node metastasis, high pathological grade, tumor size larger than 2 cm |
| Naohisa Futamura-16 |
Osteosarcoma |
MT1-MMP |
Not associated with age, gender, anatomic location, necrosis after neoadjuvant chemotherapy, or surgical stage |
| Jian Gao-43 |
Ovarian cancer |
Lewis y antigen |
Drug-resistant |
| Luís Silva Monteiro-15 |
Oral squamous cell carcinomas |
Ki-67 |
Advanced tumor stages, histological grade |
| Shaojun Zhu-41 |
Hepatocellular carcinoma |
|
No relationship between differentiation, HBV infection, significantly opposite to cirrhosis |
| Univariate |
| Hai-Gang Li-42 |
Hepatocellular carcinoma |
paxillin and syndecan-1 (no) |
Not associated with serum AFP level, HBsAg status, presence of microsatellite nodule, tumor size, presence of cirrhosis and necrosis, differentiation, presence of portal vein thrombosis and extra-hepatic metastasis |
| Wen-Chiuan Tsai -43 |
Renal cell carcinoma |
fascin |
Histological grades and clinical stages |
| Nobuyuki Hakuma-44 |
Non-Small Cell Lung Cancers |
|
Well differentiated, not associated with any of the following variables: age, gender, histology, pT or pN classification, and pathological stage |
| Wen Chiuan Tsai-45 |
Pancreatobiliary adenocarcinoma |
fascin |
Histologic grades and clinical stages |
| Wei Wu-46 |
Gallbladder carcinoma |
MMP-2 |
Nevin stages of tumor tissues, histological differentiated degree, distant metastasis |
| Daniel Buergy-47 |
Colorectal Cancer |
|
pT or pN status, metastasis |
| Ziming Du-48 |
Nasopharyngeal carcinoma |
Cav-1 |
Metastasis of the disease |
| Zhaodong Han-49 |
Renal/Bladder/Prostate carcinoma |
|
TNM stages, histological subtypes |
| H. Z. Zeng-7 |
Non-small-cell lung cancer |
|
No association (overall CD147); (membranous CD147) associated with a poor response to chemotherapy |
| Congfa Huang-9 |
Tongue squamous cell carcinoma |
HIF-1a, VEGF-A, VEGF-C, CypA |
Recurrence and node metastasis |
| Larissa Sweeny-50 |
Cutaneous Squamous Cell Carcinoma |
|
Node positive disease |
| Keiichiro Nakamura-51 |
Endometrial cancer |
|
FIGO stage, histology, depth of myometrial invasion, cervical involvement, lymph node metastasis, lymph vascular space involvement, peritoneal cytology |
| Mototaka Sato-52 |
Renal cell carcinoma |
anti-CD34 |
Pathological T stage, clinical M stage, AJCC stage, Fuhrman grade, microvessel area of immature vessels |
| Wen Chiuan Tsai-53 |
Astrocytomas |
|
WHO grades |
| Qing Yang-54 |
Hypopharyngeal Squamous Cell Carcinoma |
CD44v6; COX-2 |
T classification, lymph node metastasis and clinical stage |
| Xinwen Zhong-55 |
Lung cancer |
RACK1 |
Differentiation, Lymph node metastasis |
| Jung-Woo Choi-56 |
Urothelial carcinoma of the bladder |
MCT1, MCT4 |
High World Health Organization grade, advanced tumor node metastatis stage, and nonpapillary growth type |
| Xin-Qiong Huang-57 |
Cervical squamous cell carcinoma |
GLUT-1 |
Histopathological grade, Tumor diameter, radiation-resistant |
| Céline Pinheiro-58 |
Soft tissue sarcomas |
MCT1, MCT4 |
Disease progression |
| Younghye Kim-59 |
Clear cell renal cell carcinoma |
|
High grade, tumor necrosis, larger tumor size |
