Table 3.

The prevalence of symptoms in MHD Patients

Symptom	Number of patients reported the symptom	Percentage of patients reported the symptom	Severitya
Dry skin	242	80.4	(2.79 ± 1.24)
Itching	234	77.7	(3.41 ± 1.53)
Difficulty asleep	229	76.1	(2.70 ± 1.27)
Feel tired or lack of energy	223	74.1	(2.47 ± 1.16)
Trouble falling asleep	206	68.4	(2.57 ± 1.36)
Decrease interest in sex	201	66.8	(2.83 ± 1.57)
Dry mouth	199	66.1	(2.28 ± 1.14)
Difficulty becoming sexually aroused	195	64.8	(2.79 ± 1.60)
Difficulty concentrating	176	58.5	(2.09 ± 1.12)
Bone or joint pain	173	57.5	(2.24 ± 1.28)
Feeling irritable	173	57.5	(2.09 ± 1.18)
Worrying	172	57.1	(2.10 ± 1.16)
Muscle Soreness	161	53.5	(2.02 ± 1.13)
Cough	154	51.2	(1.89 ± 1.03)
Feeling anxious	152	50.5	(1.96 ± 1.16)
Muscle cramps	145	48.2	(1.78 ± 0.96)
Feeling sad	145	48.2	(1.93 ± 1.18)
Headache	144	47.8	(1.83 ± 1.01)
Lightheadedness or dizziness	143	47.5	(1.74 ± 0.92)
Feeling nervous	139	46.2	(1.86 ± 1.11)
Decreased appetite	130	43.2	(1.72 ± 0.94)
Constipation	128	42.5	(1.82 ± 1.11)
Shortness of breath	122	40.5	(1.71 ± 0.97)
Numbness or tingling in feet	117	38.9	(1.72 ± 1.07)
Nausea	106	35.2	(1.52 ± 0.80)
Restless legs/difficulty keeping legs still	95	31.6	(1.57 ± 0.97)
Swelling in legs	94	31.2	(1.51 ± 0.86)
Chest pain	87	28.9	(1.49 ± 0.87)
Vomiting	73	24.3	(1.36 ± 0.71)
Diarrhea	70	23.3	(1.38 ± 0.76)

^aBased on the five-point Likert scale: 0 “not at all bothersome” to 4 “bothers very much.”