Table 3.
Mean percent change in lipid profile after 12 weeks in each treatment group
Parameters (%) | ||||||||
---|---|---|---|---|---|---|---|---|
GROUP | TC value (95 % CI) | LDL-C value (95 % CI) | HDL-C value (95 % CI) | TG value (95 % CI) | VLDL-C (95 % CI) | LDL/HDL (95 % CI) | Atherogenic index (95 % CI) | |
1 | Atorvastatin | −34.0 (−36.43, −31.57) | −36.42 (−39.00, −33.80) | 34.20 (29.78, 38.62) | −30.80 (−32.74, −28.86) | −30.80 (−33.58, −28.02) | −52.66 (−62.56, −42.76) | −26.28 (−31.97, −20.59) |
2 | Proanthocyanidins (OPC) | −22.50 (−24.19, −20.81) | −23.68 (−25.50, −21.86) | 19.44 (16.30, 22.58) | −25.07 (−27.33, −22.81) | −25.05 (−26.18, −23.92) | −36.09 (−40.21, −31.97) | −18.52 (−20.26, −16.78) |
3 | Nicotinic acid (NA) | −14.90 (−15.69, −14.11) | −15.75 (−16.87, −14.63) | 26.8 (23.19, 30.41) | −19.88 (−21.48, −18.28) | −19.85 (−21.78, −17.92) | −33.57 (−37.57, −29.57) | −18.25 (−21.03, −15.47) |
4 | Pterostilbene (PT) | −26.22 (−27.59, −24.85) | −28.47 (−30.51, −26.43) | 13.69 (10.32, 17.06) | −14.7 (−15.16, −14.24) | −14.71 (−16.48, −12.94) | −37.08 (−41.58, −32.58) | −11.4 (−13.12, −9.679) |
5 | OPC : NA 30:70 | −23.36 (−24.68, −22.04) | −25.18 (−26.67, −23.69) | 36.0 (31.41, 40.59) | −25.07 (−26.62, −23.52) | −25.05 (−27.19, −22.91) | −45.02 (−49.82, −40.22) | −23.63 (−26.88, −20.38) |
6 | OPC : NA 50:50 | −25.58 (−26.81, −24.35) | −27.66 (−29.11, −26.21) | 27.27 (24.54, 30.00) | −21.32 (−23.07, −19.57) | −21.31 (−22.97, −19.65) | −43.2 (−48.02, −38.38) | −19.07 (−21.10, −17.04) |
7 | OPC : NA 70:30 | −32.13 (−33.84, −30.42) | −34.57 (−37.89, −31.25) | 29.9 (25.39, 34.41) | −27.4 (−29.81, −24.99) | −27.4 (−29.48, −25.32) | −49.64 (−57.83, −41.45) | −23.08 (−25.94, −20.22) |
8 | OPC : PT 30:70 | −36.79 (−39.00, −34.58) | −40.17 (−42.27, −38.07) | 20.09 (17.50, 22.68) | −18.16 (−18.79, −17.53) | −18.13 (−19.63, −16.63) | −50.2 (−53.74, −46.66) | −15.24 (−17.65, −12.83) |
9 | OPC : PT 50:50 | −32.13 (−34.13, −30.13) | −34.97 (−37.36, −32.58) | 27.27 (22.98, 31.56) | −21.33 (−23.07, −19.59) | −21.31 (−22.97, −19.65) | −48.9 (−54.96, −42.84) | −19.07 (−21.11, −17.03) |
10 | OPC : PT 70:30 | −35.73 (−38.01, −33.45) | −38.97 (−41.34, −36.60) | 27.45 (23.16, 31.74) | −27.38 (−29.88, −24.88) | −27.39 (−29.47, −25.31) | −49.64 (−57.82, −41.46) | −22.35 (−25.11, −19.59) |
11 | NA : PT 30:70 | −34.99 (−37.18, −32.80) | −38.0 (−39.77, −36.23) | 20.05 (17.56, 17.56) | −20.17 (−22.24, −18.10) | −20.16 (−21.41, −18.91) | −48.36 (−52.55, −44.17) | −16.15 (−17.81, −14.49) |
12 | NA : PT 50:50 | −31.71 (−33.47, −29.95) | −34.57 (−36.54, −32.60) | 31.62 (28.20, 35.04) | −22.19 (−23.68, −20.70) | −22.19 (−24.20, −20.18) | −50.30 (−57.47, −43.13) | −20.8 (−23.07, −18.53) |
13 | NA : PT 70:30 | −30.34 (−29.62, −26.82) | −33.13 (−32.21, −29.33) | 34.53 (29.17, 39.89) | −22.2 (−23.45, −20.95) | −22.2 (−23.99, −20.41) | −50.30 (−55.64, −41.48) | −21.72 (−25.18, −18.26) |
14 | OPC : NA : PT 50:30:20 | −40.49 (−42.95, −38.03) | −44.1 (−46.86, −41.34) | 37.26 (32.61, 41.91) | −27.09 (−28.92, −25.26) | −27.08 (−28.92, −25.24) | −59.30 (−68.18, −50.42) | −25.09 (−28.30, −21.88) |
15 | OPC : NA : PT 50:20:30 | −39.53 (−41.86, −37.20) | −43.13 (−45.10, −41.28) | 32.5 (29.48, 35.52) | −25.36 (−27.52, −23.20) | −23.59 (−26.15, −21.03) | −57.84 (−66.56, −49.12) | −23.45 (−25.85, −21.05) |
16 | OPC : NA : PT 20:50:30 | −37.80 (−39.74, −35.86) | −41.4 (−44.20, −38.60) | 38.99 (32.84, 45.14) | −25.07 (−25.76, −24.38) | −25.05 (−26.59, −23.51) | −57.80 (−68.45, −47.15) | −24.50 (−26.67, −22.33) |
Data is presented as mean percent change from the disease control at 95 % confidence interval