Skip to main content
. 2016 Sep 9;17(1):128. doi: 10.1186/s12882-016-0343-2

Table 1.

The top 5 enriched GO terms with the most low p-value for differentially expressed genes

Category Terms Description Count p-value Genes
BP GO:0030029 actin filament-based process 23 5.38E-07 MTSS1, ROCK1, ACTN4, AIF1, CALD1, ARF6, MYH9, CAPZB, TNNT2, ACTG1
GO:0030036 actin cytoskeleton organization 22 7.32E-07 MTSS1, ROCK1, ACTN4, AIF1, CALD1, ARPC5, MYH9, CAPZB, TNNT2, ACTG1
GO:0008285 negative regulation of cell proliferation 28 1.48E-06 AIF1, IGFBP7, PTH1R, ING1, COL4A3, BMP2, CTBP1, GAS1, CD164, TGFBR3
GO:0007010 cytoskeleton organization 31 2.17E-06 MTSS1, AIF1, CALD1, ARF6, ACTG1, PAK1, PLS3, ACTN4, ROCK1, MYH9
GO:0030832 regulation of actin filament length 11 6.01E-06 ACTR3, PFN2, CAPZA1, TMSB4X, RDX, ARF6, ARPC5, CAPZB, SPTAN1, DSTN
CC GO:0015629 actin cytoskeleton 31 2.60E-11 MTSS1, AIF1, CALD1, MYL9, ACTR3, ACTG1, ACTN4, MYO1B, MYH9, CTNNA1
GO:0005938 cell cortex 20 1.02E-08 SEPT2, ACTN4, SEPT1, CALD1, ARF6, MYH9, SEPT10, ACTG1, FNBP1, CLIC5
GO:0005856 cytoskeleton 70 1.28E-07 MTSS1, AIF1, CALD1, MYL9, ACTR3, ACTG1, ACTN4, MYO1B, MYH9, CTNNA1
GO:0044448 cell cortex part 13 1.78E-06 SEPT2, ACTN4, SEPT1, CALD1, PRKCI, MYH9, CAPZB, SEPT10, DSTN, ACTG1
GO:0043232 intracellular non-membrane-bounded organelle 104 5.54E-06 SEPT2, ACTN4, SEPT1, CALD1, PRKCI, MYH9, CAPZB, SEPT10, DSTN, ACTG1
MF GO:0008092 cytoskeletal protein binding 40 7.17E-10 MTSS1, AIF1, TNNC1, CALD1, EZR, TARDBP, ACTN4, MYO1B, SUN2, MYH9
GO:0003779 actin binding 30 5.79E-09 MTSS1, AIF1, TNNC1, CALD1, ACTN4, MYH9, PALLD, NEBL, TNNT2, PARVA
GO:0005520 insulin-like growth factor binding 6 3.80E-04 CTGF, HTRA1, IGFBP7, IGFBP2, CRIM1, CYR61
GO:0005200 structural constituent of cytoskeleton 9 6.07E-04 TNNT2, ACTG1, DMD, VIM, AGRN, ARPC5, CD2AP, ADD3, SPTAN1
GO:0050839 cell adhesion molecule binding 6 9.18E-04 EZR, PVRL2, NPTN, CTNNA1, CD2AP, CTNNB1

GO Gene Ontology, BP biological process, MF molecular function, CC cellular component