Table 2.
The results of pathway enrichment analysis for the down-regulated genes
| Category | Pathway Name | Count | p-value | Genes |
|---|---|---|---|---|
| KEGG_PATHWAY | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 11 | 1.41E-04 |
ACTG1, ATP2A2, ACTN4, DMD, DAG1, CACNB2, ITGB5, ITGA3, CTNNA1, CTNNB1… ACTN4, ROCK1, ITGB5, RDX, ITGA3, ARPC5, MYL12A, MYH9, MYL9, ACTG1… |
| KEGG_PATHWAY | Regulation of actin cytoskeleton | 19 | 1.65E-04 | |
| KEGG_PATHWAY | Hypertrophic cardiomyopathy (HCM) | 9 | 0.00575 | TNNT2, ACTG1, ATP2A2, TNNC1, DMD, DAG1, CACNB2, ITGB5, ITGA3 |
| KEGG_PATHWAY | Complement and coagulation cascades | 8 | 0.00641 | CD55, F3, CD46, CD59, C1R, SERPING1, C1S, F2R |
| KEGG_PATHWAY | Dilated cardiomyopathy | 9 | 0.00920 | TNNT2, ACTG1, ATP2A2, TNNC1, DMD, DAG1, CACNB2, ITGB5, ITGA3 |
| KEGG_PATHWAY | Pathogenic Escherichia coli infection | 7 | 0.00956 | ACTG1, EZR, ROCK1, TUBB2A, YWHAQ, ARPC5, CTNNB1 |
KEGG, Kyoto Encyclopedia of Genes and Genomes