Table 2.
Therapeutic responses of 27 RRMM patients to single-agent circularly permuted TRAIL (CPT) treatment
| Responsea | No. of patients (%) |
|---|---|
| Near-complete response (nCR) | 1 (3.7) |
| Partial response (PR) | 8 (29.6) |
| Minimal response (MR) | 4 (14.8) |
| No change (NC) | 3 (11.1) |
| Progressive disease (PD) | 11 (40.7) |
| ORR (nCR + PR) | 9 (33.3) |
| CBR (nCR + PR + MR) | 13 (48.1) |
ORR overall response rate, CBR clinical benefit rate, TRAIL tumor necrosis factor-related apoptosis-inducing ligand
aResponses were assessed according to the European Group for Blood and Marrow Transplantation criteria