Table 2.
Authors and publish time | Virology and immunologic response | Serious drug- related AEs | ||
---|---|---|---|---|
Experiment group, % (n/N) | Control group, n (%) | Experiment group, n (%) | Control group, n (%) | |
Jan van Lunzen et al. 2012. [20] | 10 mg: 91 % (48/53) 25 mg: 88 % (45/51) 50 mg: 90 % (46/5150) | EFV (600 mg): 82 % (41/50) | 0 | 2 % (1/50) |
Pedro Cahn et al. 2013. [23] | 50 mg: 71 % (251/354,378) | RAL (400 mg): 64 % (230/414) | 1 % (2/378) | 1 % (4/414) |
Francois Raffi et al. 2013. [21] | 50 mg: 88 % (361/411) | RAL (400 mg): 85 % (351/411) | <1 % (3/411) | 1 % (5/411) |
S. Walmsley et al. 2013. [22] | 50 mg: 88 % (364/414) | RAL (400 mg): 81 % (338/419) | <1 % (1/414) | 2 % (8/419) |
DTG dolutegravir, S/GSK1349572; RAL raltegravir; EFV efavirenz