Fig. 4.

Receiver operator characteristic (ROC) curve for the prediction of AKI 2/3. a Preoperative serum creatinine and eGFR. b [TIMP 2]*[IGFBP7], serum creatinine and ∆ eGFR 4 h after TAVI. c [TIMP 2]*[IGFBP7],serum creatinine and ∆ eGFR on postoperative day 1 after TAVI. d Maximum [TIMP 2]*[IGFBP7], serum creatinine and ∆ eGFR during the first 24 h after surgery. AKI = acute kidney injury, AUC = Area under the curve, IGFBP7 = insulin-like growth factor binding protein 7, KDIGO = Kidney Disease: Improving Global Outcomes; ROC = Receiver operating characteristic; RRT = renal replacement therapy, TIMP- 2 = tissue metalloproteinase 2. * defined as maximum level in the first 24 h after surgery