Table 1.
Patient characteristics in patients with AKI 2/3 compared to patients with AKI ≤2
| AKI KDIGO 2/3 | KDIGO 0/1 | p-Value | |
|---|---|---|---|
| (n = 8) | (n = 32) | ||
| Age [years] | 81.4 ± 4.2 | 80.7 ± 5.9 | n.s. |
| Male gender [n (%)] | 3 (37.5) | 13 (40.6) | n.s. |
| Weight [kg] | 76.6 ± 13.6 | 70.2 ± 11.2 | n.s. |
| Height [cm] | 167.3 ± 6.6 | 164.7 ± 8.5 | n.s. |
| Preoperative creatinine [mg/dl] | 1.18 ± 0.26 | 1.12 ± 0.24 | n.s. |
| Preoperative eGFR [ml/min/1.73 m2] | 65.6 ± 15.9 | 65.9 ± 18.1 | n.s. |
| Transapical approach [n (%)] | 6 (75.0) | 28 (87.5) | n.s. |
| SAPS | 33.8 ± 9.7 | 27.0 ± 6.7 | 0.034 |
| TISS | 23.0 ± 4.5 | 22.6 ± 4.5 | n.s. |
| LVEF [%] | 49.3 ± 16.9 | 49.3 ± 10.9 | n.s. |
| AVA [cm2] | 0.83 ± 0.32 | 0.69 ± 0.22 | n.s. |
| MPG [mmHg] | 36.8 ± 23.5 | 42.9 ± 17.2 | n.s. |
| Comorbidities [n (%)] | n.s. | ||
| Hypertension | 7 (87.5) | 24 (75.0) | n.s. |
| PHT | 1 (12.5) | 5 (15.6) | |
| Smoking | 2 (25.0) | 8 (25.0) | n.s. |
| Diabetes | 3 (37.5) | 10 (31.3) | n.s. |
| COPD | 4 (50.0) | 6 (18.8) | n.s. |
| Atrial fibrillation | 7 (87.5) | 13 (40.6) | 0.031 |
| Peripheral artery disease | 1 (12.5) | 11 (34.4) | n.s. |
| Recent myocardial infarction | 2 (25.0) | 2 (6.3) | n.s. |
| CAD | 5 (62.5) | 19 (59.4) | n.s. |
| Duration of surgery [h] | 84.09 ± 0.03 | 84.06 ± 0.02 | n.s. |
| Contrast agent [ml] | 102.1 ± 35.8 | 131.0 ± 44.7 | n.s. |
| Fluid balance on the day of surgery [ml] | 2950. 0 ± 1053.8 | 2239.3 ± 954.6 | n.s. |
| Cumulative catecholamine dosage on the day of surgery [μg/kgBW/min] | 0.12 ± 0.09 | 0.06 ± 0.08 | n.s |
| LCOS [n (%)] | 1 (12.5) | 0 (0) | n.s. |
| Sepsis [n (%)] | 2 (25.0) | 0 (0) | 0.03 |
| Septic shock [n (%)] | 1 (12.5) | 0 (0) | n.s. |
| LOS ICU/IMC [d] | 8.3 ± 4.9 | 4.9 ± 3.8 | n.s. |
| Outcomes According to VARC-2 [n (%)] | |||
| 30-d-mortality all cause | 1 (12.5) | 1 (3.1) | n.s. |
| 30-d-mortality cardiovascular | 1 (12.5) | 0 (0) | n.s. |
| Stroke/TIA 30 d | 0 (0) | 1 (3.1) | n.s. |
| Bleeding | |||
| Life-threatening/disabling | 1 (12.5) | 0 (0) | n.s. |
| Major | 0 (0) | 0 (0) | n.s. |
| Minor | 0 (0) | 0 (0) | n.s. |
| Unplanned use of CPB | 0 (0) | 0 (0) | n.s. |
| Conversion to open surgery | 0 (0) | 0 (0) | n.s. |
| Pacemaker implantation | 1 (12.5) | 0 (0) | n.s. |
| Myocardial infarction | 0 (0) | 0 (0) | n.s. |
| Procedure success | 8 (100) | 32 (100) | n.s. |
| Access site complications | |||
| minor | 0 (0) | 0 (0) | n.s. |
| major | 0 (0) | 0 (0) | n.s. |
COPD chronic obstructive pulmonary disease, SAPS Simplified Acute Physiology Score, TISS Therapeutic Intervention Scoring System, eGFR estimated glomerular filtration rate, ICU intensive care unit, IMC intermediate care unit, LVEF left ventricular ejection fraction, PHT pulmonary hypertension, CAD coronary artery disease, LCOS Low cardiac output syndrome, LOS length of stay, VARC Valve Academic Research Consortium