Table 1.
Laboratory values
| Day 0 | Day 1 | Day 2 | Day 3 | Day 4 | |
|---|---|---|---|---|---|
| Parasite count (parasites/µL) | 431,000a | 56,000 | 14,880 | Negative | Negative |
| Haemoglobin (g/dL) | 15.2 | 13.3 | 11.8 | 12.5 | 12.2 |
| Haematocrit (%) | 43.4 | 39.5 | 33.4 | 35.5 | 35.3 |
| White blood cells (×103/µL) | 8.7 | 10.9 | 10.7 | 11.5 | 11.9 |
| Platelets (×103/µL) | 24 | 28 | 29 | 52 | 104 |
| Creatinine (µmol/L) | 145 | 112 | 92 | 86 | |
| Total bilirubin (µmol/L) | 181 | 178 | 57 | ||
| Direct bilirubin (µmol/L) | 110 | 115 | 33 | ||
| Alanine aminotransferase (IU/L) | 90 | 62 | 55 | ||
| Aspartate aminotransferase (IU/L) | 146 | 160 | 71 | ||
| Bicarbonate (mmol/L) | 11 | 23.1 | 23.9 | ||
| Lactate (mmol/L) | 1.89 | 1.74 | 1.30 | ||
| Glucose (mmol/L) | 8.0 | 12.1 | 10.8 | 9.3 | |
| Cell free haemoglobin (ng/mL) | 10.2 × 105 | 0.3 × 105 | |||
| Haptoglobin (µg/mL) | <0.01 |
a Parasitaemia as reported by expert research microscopist. A total of 30 ring stage parasites, 35 trophozoites and 14 schizonts per 1000 RBCs were seen, accounting for a parasitaemia of 7.9 %, or 431,000 parasites/μL