Table 1. Pathological examination of liver and pancreas in the 3 study groups.
Liver | Pancreas | ||
---|---|---|---|
Microvesicular steatosis | Macrovesicular steatosis | Atrophy | |
N | 0.00 | 0.00 | 0.00 |
HFG | 4.88 ± 0.35a | 4.38 ± 0.74a | 3.38 ± 1.30a |
PTX | 3.13 ± 0.35b | 3.75 ± 0.89a | 0.88 ± 1.64b |
Abbreviations: N, normal group; HFG, high-fat diet plus hyperglycaemia group; PTX, high-fat diet/hyperglycaemia plus pentoxifylline treatment group. Lesion degree was graded from 1 to 5: 1 = minimal (<1%); 2 = slight (1–25%); 3 = moderate (26–50%); 4 = moderate/severe (51–75%); 5 = severe/high (76–100%)55. Values are presented as means ± SD (N = 8); superscripted letters indicate significant differences (Mann-Whitney test, P < 0.05).