Table 1. Anthropometric, biochemical and hormonal characteristics of control and T2DM groups ( ± s).
Variable | T2DM (n = 162) | NGT (n = 100) |
---|---|---|
Age (year) | 54 ± 6 | 53 ± 11 |
Male/female | 88/92 | 50/50 |
BMI (kg/m2) | 25.5 ± 4.4* | 22.7 ± 3.2 |
WHR | 0.91 ± 0.05* | 0.86 ± 0.06 |
FAT (%) | 30.0 ± 5.9* | 28.2 ± 8.4 |
SBP (mmHg) | 126 ± 11* | 117 ± 16 |
DBP (mmHg) | 75 ± 7 | 76 ± 10 |
TC (mmol/L) | 4.95 ± 0.48* | 4.78 ± 1.22 |
TG (mmol/L) | 2.15 ± 0.45* | 1.19 ± 0.72 |
FFA (μmol/L) | 0.76 ± 0.31* | 0.41 ± 0.21 |
HDL-C (mmol/L) | 1.39 ± 0.38 | 1.46 ± 0.39 |
LDL-C (mmol/L) | 2.67 ± 0.82 | 2.77 ± 0.87 |
HbA1c (%) | 8.04 ± 0.50** | 5.74 ± 0.33 |
FBG (mmol/L) | 9.17 ± 0.81** | 5.33 ± 0.63 |
2h-OGTT (mmol/L) | 17.2 ± 4.1** | 5.8 ± 0.7 |
FINS (mU/L) | 14.19 ± 3.25** | 8.94 ± 3.88 |
2h-INS (mU/L) | 40.7 ± 10.9* | 43.2 ± 21.9 |
HOMA-IR | 5.80 ± 1.50** | 2.12 ± 0.95 |
ADI (μg/L) | 33.3 ± 8.8** | 41.8 ± 13.6 |
ZAG (mg/L) | 35.6 ± 9.1** | 59.4 ± 16.2 |
NGT, normal glucose tolerance; nT2DM, type 2 diabetes mellitus; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; WHR, waist-to-hip ratio; Fat (%), the percentage of fat in vivo; FBG, fasting blood glucose; 2h-OGTT, 2-h blood glucose after glucose overload; FINS, fasting insulin; 2h-INS, 2-h insulin after glucose overload; HOMA- IR, homeostasis model assessment-insulin resistance index; FFA, free fatty acids; TG, triglyceride; TC, total cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein. ADI, adiponectin; ZAG, Zinc-α2-glycoprotein. Data are mean ± SD. *P < 0.05; **P < 0.01 compared with NGT group.