Table 3.
Multivariable logistic regression analysis of the association between change in MVPA, SED‐time and PAEE from baseline to 4–year follow‐up and CKD at four years in the ADDITION‐Plus trial cohort
| Relative risk | 95% CI | P | ||
|---|---|---|---|---|
| Model 1 | ΔSED‐time | 1.149 | 0.968–1.364 | 0.113 |
| ΔMVPA | 0.544 | 0.294–1.007 | 0.053 | |
| ΔPAEE | 0.968 | 0.941–0.995 | 0.023 | |
| Model 2 | ΔSED‐time | 1.095 | 0.887–1.352 | 0.397 |
| ΔMVPA | 0.689 | 0.333–1.428 | 0.316 | |
| Model 3 | ΔSED‐time | 1.088 | 0.867–1.365 | 0.466 |
| ΔMVPA | 0.591 | 0.272–1.282 | 0.183 | |
| ΔPAEE | 0.964 | 0.936–0.993 | 0.014 | |
Model 1 was adjusted for age, sex, socio‐economic status, baseline CKD status and baseline value of the relevant exposure.
Model 2 was further adjusted for baseline SED‐time and ΔSED‐time (when ΔMVPA was the exposure) or baseline MVPA and ΔMVPA (when ΔSED‐time was the exposure).
Model 3 was further adjusted for Δcurrent smoking status, Δwaist, ΔHbA1c, Δsystolic BP, Δtriglycerides, Δglucose‐lowering drugs, Δlipid‐lowering drugs, Δanti‐hypertensive drugs and Δaspirin from baseline to 4 years.