Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jun 8;64(2):501–507. doi: 10.1002/hep.28568

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 The Authors. HEPATOLOGY published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

BCR repertoire in IgG4‐related disease and disease controls (A,B) scatterplot showing the IgG⁺ repertoires in 34 patients suffering from IgG4‐RD (IRD01‐IRD34; A) and disease controls (B), consisting of PSC (PSC01‐PSC17; n = 17) and CA (CA01‐CA17; n = 17). Every dot represents a unique IgG⁺ clone. IgG4⁺ clones are marked in red. (C) Bar chart showing the distribution of IgG1+, IgG2+, IgG3+, and IgG4‐positive clones of all IgG+ clones within the repertoire in IgG4‐RD, PSC, and CA. (D) Bar chart showing the part of the repertoire taken up by IgG4⁺ BCRs versus IgG4^‐ BCRs in IgG4‐RD, PSC, and CA. (E) Ranks of the most dominant IgG4⁺ clones within the IgG⁺ repertoire in IgG4‐RD, PSC, and CA (P < 0.0001).