Skip to main content
. 2016 Sep 9;11(9):e0162638. doi: 10.1371/journal.pone.0162638

Fig 2. The pre-BCR components show distinct mRNA expression patterns in BCP-ALL and normal B cells.

Fig 2

(A) Heat map shows the expression patterns of the pre-BCR components in childhood BCP-ALL (GSE12995). (B) The graphs show the expression patterns of IGHM, VPREB1 and IGLL1 in 733 BCP-ALL patient samples from six cohorts (GSE12995, Blood2003, GSE177031, GSE26281, GSE13425 and GSE47051). All patient samples were evenly divided into quartiles according to the expression level of IGHM, VPREB1 or IGLL1. (C) Heat map shows the expression patterns of the pre-BCR components in a normal B-cell data set (GSE45460). HH, High Hyperdiploid; iB, immature B cells.