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. 2016 Sep 9;11(9):e0161883. doi: 10.1371/journal.pone.0161883

Fig 11. Leukocyte subsets in the colon of interleukin-10 receptor (IL-10R) neutralized SJL mice.

Fig 11

(A) Application of IL-10R antibody (Ab) leads to increased numbers of CD3+ T cells in the colon at all investigated time points. (B). An increase of CD45R+ B cells can be observed at day 21 after the first Ab application. (C) Foxp3+ regulatory T cells and (D) Iba-1+ macrophages are elevated at 7, 14, and 21 dpi. grey box with vertical lines = control animals (group “isotype”), white box with vertical lines = IL-10R blocked animals (group “IL-10R↓”). Box and whisker plot display median, minimum and maximum values as well as upper and lower quartiles, 5 animals used at all investigated time points, Wilcoxon rank-sum tests, *  =  p < 0.05.