Table 4. Mortality rate, hospitalizations and HRQoL for patients with COPD exacerbation based on the clusters at baseline (1 year period) and based on the clusters transition for a 1 year period.
Baseline | First year | 1 year later | Second year | ||||
---|---|---|---|---|---|---|---|
Cluster | HRQoL* | Mortality | Hospitalizations | Cluster | HRQoL* | Mortality | Hospitalizations |
n (%) | n (%) | n (%) | n (%) | ||||
A (n = 164) | 29.2 B,C,D (26.7–31.8) | 2 (1.2) | 16 (9.8) | A (n = 116) | 28.0 (24.4–31.5)C | 0 (--) | 6 (5.2) |
B (n = 34) | 28.9 (23.6–34.3) | 0 (--) | 3 (8.9) | ||||
C (n = 6) | 47.4 (27.6–67.2)A | 1 (16.7) | 1 (16.7) | ||||
D (n = 1) | (--) | (--) | (--) | ||||
P¥ | 0.05£ | 0.045 | 0.295 | ||||
B (n = 195) | 40.0 A,C (37.4–42.7) | 8 (4.1) | 35 (17.9) | A (n = 7) | 29.7 (12.4–47.1)C | 0 (--) | 1 (2.4) |
B (n = 140) | 36.7 (33.8–39.6)C | 5 (3.6) | 18 (12.9) | ||||
C (n = 29) | 48.4 (41.4–55.4)A,B | 7 (24.1) | 11 (37.9) | ||||
D (n = 1) | (--) | (--) | (--) | ||||
P¥ | 0.003£ | 0.003 | 0.012 | ||||
C (N = 89) | 55.1 A,B,D (51.2–59.1) | 11 (12.4) | 33 (37.1) | A (n = 3) | 66.9 (22.2–111.6) | 0 (--) | 0 (--) |
B (n = 26) | 50.1 (41.4–58.9) | 0 (--) | 8 (30.8) | ||||
C (n = 41) | 53.0 (46.7–59.3) | 7 (17.1) | 18 (43.9) | ||||
D (n = 1) | (--) | (--) | (--) | ||||
P¥ | 0.406£ | 0.117 | 0.356 | ||||
D (n = 95) | 39.6 A,C (35.7–43.5) | 16 (16.8) | 35 (36.8) | A (n = 0) | (--) | (--) | (--) |
B (n = 16) | 32.6 (23.7–41.5) | 0 (--) | 4 (25.0) | ||||
C (n = 10) | 52.0 (36.2–67.9) | 4 (40.0) | 6 (60.0) | ||||
D (n = 49) | 36.5 (30.7–42.3) | 7 (14.3) | 10 (20.4) | ||||
P¥ | 0.05 | 0.021 | 0.039 | ||||
P¥ | <0.001 | <0.001 | <0.001 |
* HRQoL is measured with the total dimension score of the St. George´s Respiratory Questionnaire
¥ Chi-square test for mortality and hospitalizations and ANOVA for HRQoL are shown. Statistically significant differences between clusters are indicated with the corresponding superscript
£ Cluster D is excluded from the pairwise comparisons.
Results of groups with only one individual were not included.