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. 2016 Sep 9;11(9):e0162226. doi: 10.1371/journal.pone.0162226

Table 2. Effects of CBM interventions, compared to control, at posttest and follow-up, for addiction outcomesa.

Variable n g 95% CI I2 I2 95% CI NNT pb
Addiction (all measures) 24 0.08 -0.02 to 0.18 0 0~40 21.74
One ES per study (only highest) 24 0.11 0.009 to 0.20 0 0~40 16.13
One ES per study (only lowest) 24 0.05 -0.05 to 0.15 0 0~40 35.71
Established outcome measures only 21 0.09 -0.02 to 0.20 0 0~41 20
Comparisons with increase bias interventions excludedc 18 0.04 -0.07 to 0.15 0 0~44 45.45
Studies of CBM combined with another interventiond 4 0.06 -0.16 to 0.28 7 0~70 29.41
Subgroup analysise
Addiction type Alcohol 17 0.10 -0.01 to 0.22 0 0~45 17.86 0.459
Smoking 7 0.02 -0.15 to 0.20 0 0~58 83.33
Sample type Consumers 20 0.08 -0.03 to 0.19 0 0~42 21.74 0.979
Patients 4 0.07 -0.19 to 0.34 30 0~76 25
Delivery settingf Laboratory 15 0.07 -0.06 to 0.21 0 0~46 25 0.999
Home 4 0.07 -0.15 to 0.28 0 0~68 25
Clinic 4 0.07 -0.19 to 0.34 30 0~76 25
Bias targetedg Approach 7 0.07 -0.08 to 0.23 0 0~58 25 0.437
Attentional 12 0.03 -0.12 to 0.18 0 0~50 62.5
Inhibition 4 0.23 -0.04 to 0.50 0 0~68 7.69
Number of sessions Single 11 0.07 -0.07 to 0.21 0 0~51 25 0.867
Multiple 13 0.09 -0.05 to 0.22 0 0~49 20
Craving 18 0.05 -0.06 to 0.16 0 0~44 35.71
One ES per study (only highest) 18 0.08 -0.03 to 0.20 2 0~44 21.74
One ES per study (only lowest) 18 0.02 -0.09 to 0.14 0 0~44 83.33
Established outcome measures only 14 0.05 -0.09 to 0.19 0 0~49 35.71
Comparisons with increase bias interventions excludedh 14 0.02 -0.11 to 0.14 0 0~47 83.33
Studies of CBM combined with another interventiond 4 0.03 -0.32 to 0.38 56 0~83 62.5
Subgroup analysise
Addiction type Alcohol 12 0.07 -0.07 to 0.20 0 0~50 25 0.798
Smoking 6 0.03 -0.22 to 0.28 27 0~71 62.5
Sample type Consumers 14 0.05 -0.08 to 0.19 0 0~47 35.71 0.908
Patients 4 0.03 -0.32 to 0.38 56 0~83 62.5
Delivery setting Laboratory 12 0.06 -0.09 to 0.21 0 0~50 29.41 0.972
Home 2 0.02 -0.35 to 0.39 0 N/Ai 83.33
Clinic 4 0.03 -0.32 to 0.38 56 0~83 62.5
Bias targetedj Approach 6 0.10 -0.07 to 0.28 0 0~61 17.86 0.36
Attentional 10 -0.01 -0.19 to 0.16 11 0~58 166.67
Number of sessions Single 8 0.04 -0.15 to 0.22 0 0~56 45.45 0.895
Multiple 10 0.05 -0.10 to 0.21 10 0~57 35.71
Addiction (all measures)- follow-up 7 0.18 0.03 to 0.32 0 0~58 9.80
One ES per study (only highest) 7 0.18 0.04 to 0.32 0 0~58 9.80
One ES per study (only lowest) 7 0.16 0.02 to 0.31 0 0~58 11.11
Established outcome measures only 7 0.18 0.04 to 0.32 0 0~58 9.80
Studies of CBM combined with another interventiond 5 0.19 0.04 to 0.34 0 0~64 9.43
Subgroup analysise
Addiction type Alcohol 5 0.18 0.03 to 0.33 0 0~64 9.80 0.933
Smoking 2 0.16 -0.23 to 0.56 0 N/Ai 11.11
Sample type Consumers 3 0.09 -0.28 to 0.46 0 0~73 20 0.608
Patients 4 0.19 0.04 to 0.34 0 0~68 9.43
Bias targeted Approach 3 0.20 0.04 to 0.36 0 0~73 8.93 0.565
Attentional 4 0.10 -0.20 to 0.40 0 0~68 17.86

Note.

a All results are reported with Hedges g, using a random effects model

b The p levels in this column indicate whether the difference between the ESs in the subgroups is significant (significant results are marked with italic)

c Attwood et al., 2008; Field et al., 2005; Houben et al., 2011; Houben et al., 2012; WiersRW et al., 2010; Woud et al., 2015

d Begh et al., 2015; Lopes et al., 2014; Schoenmakers et al., 2010; Wiers et al., 2011

e Subgroup analysis were conducted using a mixed effects model.

f One study (Boendermarker et al. 2015 Study 1) gave participants a choice between home and laboratory delivery

g One study (Woud et al., 2015) used a different type of CBM (CBM for interpretation bias)

h Attwood et al., 2008; Field et al., 2005; WiersRW et al., 2010; Woud et al., 2015

i Confidence intervals around I2 cannot be calculated if there are fewer than 3 groups

j The subgroups targeting inhibition and respectively interpretation bias only had one study

n = number of trials; NNT = numbers needed to treat; N/A not available. Underlined NNT values indicate negative ES values (the direction of the effect favored the control group)