Table 3. Effect of EL 2037T/C genotypes on serum lipid levels (TT vs. TC+CC).
Genotypes | TC (mmol/L) | TG (mmol/L) | HDL-C (mmol/L) | LDL-C (mmol/L) | Apo A1 (g/L) | ApoB (g/L) | LP(a) (g/L) |
---|---|---|---|---|---|---|---|
All # | |||||||
TT (n = 602) | 4.51± 0.98 | 1.82± 1.22 | 1.09± 0.29 | 2.73± 0.82 | 1.22± 0.26 | 0.92± 0.27 | 0.23± 0.27 |
TC+CC (n = 404) | 4.56± 0.98 | 1.87± 1.43 | 1.14± 0.33 | 2.74± 0.83 | 1.22± 0.25 | 0.93± 0.31 | 0.24± 0.30 |
P | 0.794 | 0.831 | 0.023 | 0.884 | 0.748 | 0.736 | 0.452 |
CAD subgroup | |||||||
TT (n = 435) | 4.54± 1.01 | 1.80± 1.19 | 1.07± 0.27 | 2.81± 0.86 | 1.21± 0.27 | 0.93± 0.27 | 0.23± 0.26 |
TC+CC (n = 257) | 4.55± 0.97 | 1.99± 1.54 | 1.07± 0.29 | 2.80± 0.89 | 1.19± 0.23 | 0.95± 0.30 | 0.26± 0.29 |
P | 0.666 | 0.244 | 0.846 | 0.896 | 0.349 | 0.529 | 0.123 |
Control subgroup | |||||||
TT (n = 167) | 4.44± 0.89 | 1.86± 1.31 | 1.16± 0.32 | 2.53± 0.68 | 1.24± 0.21 | 0.89± 0.25 | 0.23± 0.27 |
TC+CC (n = 147) | 4.58± 0.99 | 1.66± 1.21 | 1.25± 0.37 | 2.62± 0.72 | 1.28± 0.26 | 0.89± 0.32 | 0.21± 0.31 |
P | 0.177 | 0.103 | 0.016 | 0.195 | 0.139 | 0.914 | 0.500 |
Male subgroup | |||||||
TT (n = 396) | 4.42± 1.00 | 1.81± 1.34 | 1.06± 0.29 | 2.70± 0.88 | 1.17± 0.23 | 0.91± 0.28 | 0.22± 0.26 |
TC+CC (n = 262) | 4.41± 0.92 | 1.82± 1.34 | 1.08± 0.32 | 2.68± 0.82 | 1.20± 0.28 | 0.90± 0.28 | 0.23± 0.26 |
P | 0.497 | 0.643 | 0.481 | 0.794 | 0.191 | 0.909 | 0.572 |
Female subgroup | |||||||
TT (n = 206) | 4.69± 0.92 | 1.89± 1.20 | 1.16± 0.28 | 2.78± 0.76 | 1.27± 0.22 | 0.94± 0.26 | 0.24± 0.28 |
TC+CC (n = 142) | 4.85± 1.02 | 1.87± 1.35 | 1.20± 0.31 | 2.87± 0.82 | 1.28± 0.24 | 0.97± 0.32 | 0.28± 0.36 |
P | 0.450 | 0.304 | 0.218 | 0.287 | 0.759 | 0.366 | 0.302 |
< 60 years subgroup | |||||||
TT (n = 230) | 4.56± 1.01 | 2.02± 1.51 | 1.09± 0.29 | 2.72± 0.85 | 1.22± 0.22 | 0.93± 0.27 | 0.23± 0.28 |
TG+GG (n = 147) | 4.49± 0.89 | 1.93± 1.51 | 1.15± 0.33 | 2.66± 0.73 | 1.23± 0.26 | 0.91± 0.33 | 0.21± 0.28 |
P | 0.499 | 0.253 | 0.071 | 0.484 | 0.643 | 0.629 | 0.523 |
≥ 60 years subgroup | |||||||
TT (n = 372) | 4.48± 0.97 | 1.69± 0.99 | 1.10± 0.28 | 2.74± 0.81 | 1.21± 0.28 | 0.91± 0.26 | 0.23± 0.25 |
TG+GG (n = 257) | 4.61± 1.02 | 1.84± 1.39 | 1.13± 0.33 | 2.78± 0.88 | 1.21± 0.25 | 0.93± 0.30 | 0.26± 0.31 |
P | 0.286 | 0.491 | 0.139 | 0.501 | 0.933 | 0.402 | 0.156 |
#: Patients absent of lipid profiles was excluded.