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. 2016 Sep 9;11(9):e0162338. doi: 10.1371/journal.pone.0162338

Fig 6. Loss of KRIT1 in PLCε depleted HPAEC prevents rescue by 8-pCPT-2′-O-Me-cAMP-AM and wild type PLCε.

Fig 6

A) HRP leak through HPAEC monolayer infected with negative control (NC) or PLCε siRNA ± anti-KRIT1 siRNA or 1μM 8-pCPT-2′-O-Me-cAMP-AM (cPT-2OMe). Data shown are the mean HRP concentration, ± SEM. n = 9, p<0.0001 by ANOVA, *p<0.001 by post-hoc test vs. PLCε siRNA infected cells. n.s., non-significant. B) HRP leak through HPAEC monolayer infected with negative control (NC) or PLCε siRNA ± anti-KRIT1 siRNA or siRNA resistant PLCε (WT PLCε). Data shown are the mean HRP concentration, ± SEM. n = 9, p<0.0001 by ANOVA, n.s., non-significant.