Figure 4.

Cytotoxic effect of Fuc-liposome-SN38 on colorectal cancer cell lines. A) Colo205, Ls174T cells were treated with Fuc-liposome-(F50) or liposome-(F0) containing SN38 (0.2 µM) for two hours, washed, incubated for 72 hours, and cell viability was measured by BrdU assay. Percent of viable cells was presented as compared with no treatment. B) Cells were treated with F50-liposome containing SN38 for two hours, then washed and incubated for 72 hours. Cell viability was measured by BrdU assay. The experiments were performed in triplicate and repeated twice. Statistical analysis was performed by t tests (two-sided); error bar = SD. *P < .05.