Table 1.

Gaps in our knowledge of apoC-III

1. Importance of apoC-III for VLDL secretion in humans

2. Role of apoC-III isoforms for function and pathophysiology

3. Factors regulating apoC-III expression: role of hormones and external factors

4. Role of apoC-III on HDL and HDL subspecies

5. ApoC-III as a potential biomarker of the residual risk of CVD

6. Role of apoC-III in intestinal lipid metabolism