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. 2016 Oct 4;39(10):959–976. doi: 10.1007/s40264-016-0434-9

Table 3.

Laboratory monitoring of included International epidemiologic Databases to Evaluate AIDS (IeDEA) facilities

Category and variables West Africa (n = 21) Southern Africa (n = 19) East Africa (n = 43) Central Africa (n = 12a) South America (n = 7) Asia (n = 28b) North America (n = 7c) Total (n = 137)
HIV RNA PCR
 On site 5 (23.8) 0 (0) 5 (11.6) 7 (58.3) 4 (57.1) 18 (64.3) 5 (71.4) 44 (32.1)
 Off site 7 (31.8) 0 (0) 23 (53.5) 0 (0) 2 (28.6) 5 (17.9) 2 (28.6) 39 (28.5)
 Test not available 1 (4.8) 0 (0) 10 (23.3) 5 (41.7) 0 (0) 1 (3.6) 0 (0) 17 (12.4)
 Missing 8 (38.1) 19 (100) 5 (11.6) 0 (0) 1 (14.3) 4 (14.3) 0 (0) 37 (27.0)
 Turnaround time (range) 1–60 Unknown/missing 7–60 14–30 7–60 1–60 1–10 1–60
HIV DNA PCR
 On site 3 (14.3) 0 (0) 7 (16.3) 3 (25) 2 (28.6) 9 (32.1) 1 (14.3) 25 (18.2)
 Off site 8 (38.1) 0 (0) 33 (76.7) 0 (0) 2 (28.6) 8 (28.6) 1 (14.3) 52 (37.9)
 Test not available 2 (9.5) 0 (0) 3 (7) 7 (58.3) 0 (0) 3 (10.7) 0 (0) 15 (10.9)
 Missing 8 (38.1) 19 (100) 0 (0) 2 (16.7) 3 (42.9) 8 (28.6) 5 (71.4) 45 (32.8)
 Turnaround time (range) 8–30 Unknown/missing 7–30 30 14–60 3–60 4–10 3–60
CD4+ count
 On site 11 (52.4) 0 (0) 17 (39.5) 9 (75) 6 (85.7) 24 (85.7) 5 (71.4) 72 (52.6)
 Off site 3 (14.3) 0 (0) 26 (60.5) 3 (25) 1 (14.2) 4 (14.3) 2 (28.6) 39 (28.5)
 Test not available 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
 Missing 7 (33.3) 19 (100) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 26 (19.0)
 Turnaround time (range) 1–100 Unknown/missing 1–30 1–7 1–15 1–14 1–5 1–100
Hemoglobin
 On site 12 (57.1) 0 (0) 38 (88.4) 12 (100) 7 (100) 25 (89.3) 5 (71.4) 99 (72.3)
 Off site 2 (9.5) 0 (0) 4 (9.3) 0 (0) 0 (0) 3 (10.7) 2 (28.6) 11 (8.0)
 Test not available 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) 0 (0)
 Missing 7 (33.3) 19 (100) 1 (2.3) 0 (0) 0 (0) 0 (0) 0 (0) 27 (19.7)
 Turnaround time (range) 1–100 Unknown/missing 1–30 <1–3 1–15 <1–3 <1–2 <1–100
Total lymphocyte count
 On site 11 (52.4) 0 (0) 16 (37.2) 10 (83.3) 7 (100) 24 (85.7) 4 (57.1) 72 (52.6)
 Off site 3 (14.3) 0 (0) 26 (60.5) 1 (8.3) 0 (0) 3 (10.7) 3 (42.9) 36 (26.3)
 Test not available 0 (0) 0 (0) 0 (0) 1 (8.3) 0 (0) 0 (0) 0 (0) 0 (0)
 Missing 7 (33.3) 19 (100) 1 (2.3) 0 (0) 0 (0) 1 (3.6) 0 (0) 28 (20.4)
 Turnaround time (range) 1–100 Unknown/missing 1–30 1–3 1–15 <1–14 <1–2 <1–100
ALT/AST
 On site 11 (52.4) 0 (0) 16 (37.2) 7 (58.3) 7 (100) 24 (85.7) 5 (71.4) 70 (51.1)
 Off site 3 (14.3) 0 (0) 26 (60.5) 2 (16.7) 0 (0) 3 (10.7) 2 (28.6) 36 (26.3)
 Test not available 0 (0) 0 (0) 0 (0) 3 (25.0) 0 (0) 0 (0) 0 (0) 0 (0)
 Missing 7 (33.3) 19 (100) 1 (2.3) 0 (0) 0 (0) 1 (3.6) 0 (0) 28 (20.4)
 Turnaround time (range) 1–100 Unknown/missing 1–30 1–3 1–15 <1–2 1–2 <1–100
Cholesterol
 On site 9 (42.9) 0 (0) 6 (14) 5 (41.7) 7 (100) 25 (89.3) 5 (71.4) 57 (41.6)
 Off site 5 (23.8) 0 (0) 32 (74.4) 4 (33.3) 0 (0) 3 (10.7) 2 (28.6) 46 (33.6)
 Test not available 0 (0) 0 (0) 3 (7) 2 (16.7) 0 (0) 0 (0) 0 (0) 5 (3.6)
 Missing 7 (33.3) 19 (100) 2 (4.7) 1 (8.3) 0 (0) 0 (0) 0 (0) 29 (21.2)
 Turnaround time (range) 1–100 Unknown/missing <1–30 1–3 1–15 <1–7 <1–7 <1–100
Creatinine
 On site 11 (52.4) 0 (0) 15 (34.9) 8 (66.7) 7 (100) 25 (89.3) 5 (71.4) 71 (51.8)
 Off site 3 (14.3) 0 (0) 27 (62.8) 1 (8.3) 0 (0) 3 (10.7) 2 (28.6) 36 (26.3)
 Test not available 0 (0) 0 (0) 0 (0) 2 (16.7) 0 (0) 0 (0) 0 (0) 2 (1.5)
 Missing 7 (33.3) 19 (100) 1 (2.3) 1 (8.3) 0 (0) 0 (0) 0 (0) 28 (20.4)
 Turnaround time (range) 1–100 Unknown/missing 1–30 1–3 1–15 <1–3 <1–1 <1–100
Lactate
 On site 7 (33.3) 0 (0) 6 (14) 2 (16.7) 5 (71.4) 21 (75) 5 (71.4) 46 (33.6)
 Off site 2 (9.5) 0 (0) 31 (72.1) 2 (16.7) 1 (14.3) 7 (25) 2 (28.6) 45 (32.8)
 Test not available 3 (14.3) 0 (0) 3 (7) 6 (50) 0 (0) 0 (0) 0 (0) 12 (8.8)
 Missing 9 (42.9) 19 (100) 3 (7) 2 (16.7) 1 (14.3) 0 (0) 0 (0) 34 (24.8)
 Turnaround time (range) <1–21 Unknown/missing 1–30 1–3 1–2 <1–3 <1–2 <1–30

The data are presented as n (%). No data were available for the following laboratory tests: serum albumin, INR, alkaline phosphate, triglycerides, high-density lipoprotein, low-density lipoprotein, glucose, platelet count, total white blood count, urine albumin, urine glucose

ALT/AST alanine transaminase/aspartate transaminase, INR international normalized ratio, PCR polymerase chain reaction

aCentral Africa has 15 facilities but no data were available for three facilities

bAsia–Pacific region has 29 facilities but no data were available for one facility

cNorth America has eight facilities but no data were available for one facility